Description

Stanozolol is a white suspension for Intramuscular use. Each ml contains Stanozolol Aqua Suspension 50 mg. Stanozolol is Odorless, crystalline powder. Insoluble in water; soluble in dimethylformamide; sparingly soluble in alcohol and in chloroform; slightly soluble in ethyl acetate and in acetone; very slightly soluble in benzene. Its empirical formula is C21H32N2O and molecular weight is 328.49.

Pharmacodynamics

Anabolic steroids are synthetic derivatives of Testosterone. Stanozolol has been found to increase low-density lipoproteins and decrease high-density lipoproteins. These changes are not associated with any increase in total cholesterol or triglyceride levels and revert to normal on discontinuation of treatment. Hereditary angioedema (HAE) is an autosomal dominant disorder caused by a deficient or non-functional C1 esterase inhibitor (C1INH) and clinically characterized by episodes of swelling of the face, extremities, genitalia, bowel wall, and upper respiratory tract. In small clinical studies, Stanozolol was effective in controlling the frequency and severity of attacks of angioedema and in increasing serum levels of C1INH and C4. Stanozolol is not effective in stopping HAE attacks while they are under way. The effect of Stanozolol on increasing serum levels of C1INH and C4 may be related to an increase in protein anabolism.

Pharmacokinetic

Reverses catabolic processes and negative nitrogen balance by promoting protein anabolism and stimulating appetite if there is concurrently a proper intake of calories and proteins.

Indications and Usage

Hereditary Angioedema: Stanozolol is indicated prophylactically to decrease the frequency and severity of attacks of angioedema.

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