Description

Each ml of Testosterone Propionate contains Testosterone Propionate 100mg in oily base quantity sufficient.

Pharmacological classification

Androgenic Hormone.

Mechanism of action

Testosterone is secreted from Leydig cell of testes. It is responsible for development of secondary sex characters in males at the time of puberty and subsequent maintenance of spermatogenesis during reproductive life of males. It binds to intracellular receptors in target cells where as the hormone receptor complex translocates to nucleus where it attaches to specific binding sites on the chromosomes. This leads to increased synthesis of mRNA and protein.

Pharmacokinetic properties

Testosterone propionate is oil-based injectable testosterone. Testosterone Propionate is having anabolic as well as androgenic properties. The Propionate esters has shorter half life compared to cypionate & enanthate esters. Testosterone proprionate has a duration of effect of 1 to 2 days. Therefore Testosterone Propionate is much faster acting than othertestosterone esters such as cypionate orenanthate. Propionate is only a quickly effective testosterone that must be injected more often, and requires a much more frequent dosing schedule in order to maintain stable blood levels, Testosterone is 98% bound to a specific testosterone-estradiol binding globulin in plasma, and about 2% is free and about 90% of a dose of testosterone is excreated in the urine as glucuronic and sulphuric acid ie.,conjugates of testosterone and its metabolites, about 6% of a dose is excreated in the feaces, mostly in the conjugated form. Inactivation of testosterone occurs primarily in the liver. Testosterone is metabolized to various 17-keto steroids.

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